As the lab takes shape we say goodbye 2023 and hello 2024 - which looks set to be an awesome year.
How do malaria parasites move? Over the last 5+ yrs our lab has been working with the great teams of Kathy Trybus (University of Vermont) and Anne Houdusse (Institut Curie) to define the components of the motor https://doi.org/10.1074/jbc.M117.813972, provide a first glimpse of its structure https://doi.org/10.1038/s41467-019-11120-0, then complete it https://doi.org/10.7554/eLife.60581, and now finally (just out) drug it https://doi.org/10.7554/eLife.60581!
Confocal microscopy imaging of the Anopheles mosquito midgut. Labeled with DAPI (grey nuclei) and Phalloidin (actin, red). From Angrisano et al (2012) IJP.
As the lab takes shape we say goodbye 2023 and hello 2024 - which looks set to be an awesome year.